Genes Driving the Spread of Prostate Cancer
A recent study, published in Nature Cancer, identified 16 genes that work together to drive the spread of prostate cancer. Researchers from Rutgers University in New Jersey analysed prostate cancer cells taken from both mice and humans. They found certain gene patterns were associated with prostate cancer spreading to other parts of the body, including the bones. Screening for these genes in people diagnosed with prostate cancer could identify those who are most at risk of developing advanced disease and help inform treatment options. Dr Antonina Mitrofanova, one of the researchers, explained: ‘Our results show that molecular profiling at the time of diagnosis can help inform more personalised therapy leading to better outcomes for those with this advanced form of disease.’ The researchers also believe the genes could be used to identify which patients are more likely to respond to hormone therapies.