The androgen receptor
Prostate cancer is the most commonly diagnosed cancer in the UK. Black men are twice as likely to be diagnosed with prostate cancer compared to White men, and 2.5 times more likely to die from the disease, more research is needed to understand what causes this disparity.
The androgen receptor is a protein known to be key in the growth and spread of prostate cancer. Male hormones like testosterone drive the growth and spread of prostate cancers by attaching to the androgen receptor. This ‘switches on’ the receptor and it sends messages to the cancer cell to tell it to grow and divide. Previous research has shown that androgen receptor levels are higher in Black men, but at the moment, we don’t know why this is.
1 in 4 Black men will be diagnosed with