Project No. 02

Prostate Cancer Stem Cells

Investigating prostate cancer to find safer therapies and better diagnoses

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S c r o l l   R i g h t

The Project

The Stem Cells project is working to repurpose off-the-shelf drugs to treat prostate cancer.

How?

After discovering that a signalling system in prostate cancer stem cells are overactive, which causes them to multiple uncontrollably and spread around the body. Dr Ahmed and his team are working to use existing drugs to inhibit this.

The Medicine

The Membrane Potential Regulating Compounds (MPRCs) are existing drugs that have been shown to inhibit the spread of cancer cells.

What could this achieve?

Because the drugs are already available to treat other illnesses, we know they are safe and very cheap, meaning they could be used to stop the spread of cancer cells relatively quickly.

The Future

Dr Ahmed hopes to identify three drugs to test in chemical trials. The wealth of data on these drugs mean the treatment could be available relatively soon.

The Project

The Stem Cells project is working to repurpose off-the-shelf drugs to treat prostate cancer.

How?

After discovering that a signalling system in prostate cancer stem cells are overactive, which causes them to multiple uncontrollably and spread around the body. Dr Ahmed and his team are working to use existing drugs to inhibit this.

The Medicine

The Membrane Potential Regulating Compounds (MPRCs) are existing drugs that have been shown to inhibit the spread of cancer cells.

What could this achieve?

Because the drugs are already available to treat other illnesses, we know they are safe and very cheap, meaning they could be used to stop the spread of cancer cells relatively quickly.

The Future

Dr Ahmed hopes to identify three drugs to test in chemical trials. The wealth of data on these drugs mean the treatment could be available relatively soon.

Project Start

May 2018

Research Facility

Centre for Stem Cells and Regenerative Medicine, King’s College London

Budget

£100,000/year

End

April 2023

Dr Aamir Ahmed

PCRC Team Leader

After completion of a prestigious Wellcome Trust Fellowship at the University College London, Aamir was recruited to lead the Prostate Cancer and Stem Cell Group at the same institution. The research group moved to the Centre for Stem Cell and Regenerative Medicine at King’s College London in 2015. Aamir also acts as the Director of Research for the Prostate Cancer Research Centre charity. A curious (inquisitive not strange – or so he says!) fellow by nature, Aamir thinks he was very lucky to have carved out a career path that allows him to satisfy his innate curiosity. When not thinking about better ways to diagnose and treat prostate cancer, Aamir spends time communicating science and scientific research, writing, or struggling with sports such as squash, tennis and cricket.

Help us fund a future for men and their families

As a small charity, we can focus the majority of our funds on research.

Support Us

Support the Prostate Cancer Stem Calls Project

Any donation you can make will help fund this cutting-edge, life-saving research.

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